Zoledronic Acid Shows Lasting Clinical And Anticancer Benefits In Premenopausal Women

tD33NAt

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Mar 24, 2008
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Analyses at 62 months, or more than two years after treatment completion, confirm and extend the durable clinical and anticancer benefits of the bisphosphonate zoledronic acid that were reported at the 48-month follow-up in the Austrian Breast and Colorectal Cancer Study Group Trial 12 (ABCSG-12) trial. In the ABCSG-12 trial, 1,803 premenopausal women with endocrine-responsive early breast cancer were randomized to goserelin (3.6 mg q28d) and tamoxifen (20 mg/d) or anastrozole (1 mg/d) ± zoledronic acid (4 mg q6mo) for 3 years...


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