Molecules Designed By Computer Point To New Therapy For Cystic Fibrosis

Thread starter tD33NAt
Start date Apr 21, 2012
Tags

computer cystic designed fibrosis molecules point therapy

Apr 21, 2012

tD33NAt

Active member

By developing software that uses 3-D models of proteins involved in cystic fibrosis, a team of scientists at Duke University has identified several new molecules that may ease the symptoms of the disease. Computer algorithms created by the team predict how well a given molecular structure will block a basic protein-protein interaction known to occur in cystic fibrosis. To test the predictions, the scientists synthesized the molecules and measured how well they attached to one of the proteins in that interaction...