Even with access to health care, African-American women are less likely to receive the vaccine for human papillomavirus (HPV), which reduces the risk for cervical cancer, according to a study by researchers at the University of Pittsburgh School of Medicine. The findings, published today in the...
A new clinical research study at Roswell Park Cancer Institute (RPCI) will assess the safety and efficacy of a novel immunotherapy approach to treating advanced melanoma. Developed at RPCI by Roswell Park researchers, the investigational vaccine shows promise for treating tumors in patients with...
Approximately 13 million illnesses and over 110,00 hospitalizations may have been averted by the flu vaccine over the last 6 years in the U.S, according to calculations published in the open access journal PLOS ONE by Deliana Kostova and colleagues from the U.S Centers for Disease Control and...
An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report. The treatment, developed at Duke and tested in an ongoing phase 1 study, capitalizes on...
The University of Gothenburg Vaccine Research Institute (GUVAX) announces successful results in a placebo controlled phase I study of an oral, inactivated*Escherichia coli*diarrhea vaccine.
Enterotoxigenic*Escherichia coli*(ETEC) bacteria are the primary cause of diarrhea in children living in...
A team of NIH scientists has developed a new tool to identify broadly neutralizing antibodies (bNAbs) capable of preventing infection by the majority of HIV strains found around the globe, an advance that could help speed HIV vaccine research. Scientists have long studied HIV-infected...
Love Oral Sex? Get Your HPV Vaccine, Because HPV Could Lead To Mouth, Head & Neck Can
Researchers at Australia's University of NSW might have stumbled upon something pretty interesting (or depressing): there have been higher incidences of oesophageal cancer, with rates higher in men (especially...
IDRI (Infectious Disease Research Institute), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc. (TSX: MDG; OTCQX: MDCGF), a biopharmaceutical company focused on developing highly effective...
Delegates at a conference in the US this week are hearing about early results of a trial of a new personalized ovarian cancer vaccine that offers new hope for the large number of patients who relapse after treatment. Three-quarters of trial patients who received the new two-step immunotherapy...
Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson Cancer Center report in Nature Medicine. A common substance used in many...
Chilean scientists are working on an alcohol "vaccine" that could help treat alcoholism by making drinkers feel hungover and awful from just a few sips*of beer, liquor or wine. The drug, which is still in the trial phase, essentially turns off the liver's ability to metabolize alcohol. More »...
The US Food and Drug Administration (FDA) has approved a new 4-strain seasonal flu vaccine from GlaxoSmithKline plc (GSK), the company announced on Monday. Fluarix Quadrivalent is approved for use in adults, plus children aged 3 and over, to protect them from disease caused by influenza virus...
The Texas Biomedical Research Institute in San Antonio has applied for a patent for a genetically-engineered vaccine strategy to prevent HIV infection that targets the outer layers of body structures that are the first sites of contact with the virus. Designed to be a single dose and last a...
The FDA has approved Flucelvax, the first seasonal vaccine licenced in the USA made with the use of cultured animal cells, instead of fertilized chicken eggs. The FDA (Food and Drug Administration) has approved Flucelvax to protect patients aged at least 18 years from seasonal flu. Flucelvax's...
A new conjugate vaccine is highly effective (93-100%) at preventing invasive pneumococcal disease (IPD; meningitis, sepsis, bacteremic pneumonia, and other blood-borne infections) in infants younger than 2 years who are the most vulnerable to infection, according to new research published Online...
A team of Cardiff University scientists is leading new research to develop a vaccine against anthrax to help counteract the threat of bioterrorism. Working with scientists from the Republic of Georgia, Turkey and the USA, Professor Les Baillie from Cardiff University's School of Pharmacy and...
An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Immunotherapy, published online. Median survival in a Phase I clinical trial at...
Malaria parasites evolving in vaccinated laboratory mice become more virulent, according to research at Penn State University. The mice were injected with a critical component of several candidate human malaria vaccines that now are being evaluated in clinical trials. "Our research shows...
Early analysis from the world's first ever efficacy trial of an experimental vaccine against dengue fever shows promising results. In a study involving 4,000 children in Thailand, the vaccine appeared to prevent infection by three of the four circulating strains of the virus and showed an...
One of the challenges to HIV vaccine development has been the lack of an animal model that accurately reflects the human immune response to the virus and how the virus evolves to evade that response. In Science Translational Medicine, researchers from the Ragon Institute of Massachusetts General...