When ductal carcinoma in situ (DCIS, a preinvasive malignancy of the breast) is described as a high-risk condition rather than cancer, more women report that they would opt for nonsurgical treatments, according to a research letter by Zehra B. Omer, B.A., of Massachusetts General Hospital -...
Over half of patients saw an improvement after being treated with biological therapies for inflammatory bowel disease (IBD). Data from the first national report of biological therapies shows that 62% of adult patients and 73% of paediatric patients saw the severity of their disease decrease...
Oncopeptides AB, a company working to enhance oncology therapies, today announced that the first patient has been dosed as part of a Phase II study in multiple myeloma patients with its drug candidate melflufen (previously called J1). The trial is an open-label Phase II study designed to...
Haloperidol, an antipsychotic drug used in many hospitals to treat delirium in critically ill patients, is no more effective than placebo in reducing the number of days that critically ill patients spend either delirious or in a coma, according to new research published in The Lancet Respiratory...
CHOP researchers advance stem cell studies in a childhood leukemia and diamond blackfan anemia First produced only in the past decade, human induced pluripotent stem cells (iPSCs) are capable of developing into many or even all human cell types. In new research, scientists reprogrammed skin...
About half of a small group of patients with fibromyalgia - a common syndrome that causes chronic pain and other symptoms - was found to have damage to nerve fibers in their skin and other evidence of a disease called small-fiber polyneuropathy (SFPN). Unlike fibromyalgia, which has had no known...
A higher predicted total lung capacity ratio, suggestive of oversized donor lungs, is associated with improved survival following lung transplantation, primarily among patients who undergo double-lung (bilateral) transplants, according to a new study in the August 2013 issue of The Annals of...
How does a doctor tackle the delicate issue of end-of-life care planning with a patient? With an aging population and people living longer with chronic illness, it is increasingly important for patients and family members to decide how they and their loved ones would like to spend their final...
Prosthetic valve endocarditis (inflammation and infection involving the heart valves and lining of the heart chambers) remains associated with a high one-year mortality rate and early valve replacement does not appear to be associated with lower mortality compared with medical therapy according...
"More than a third of Parkinson's patients suffer from dementia," Prof Dr Heinz Reichmann told more than 3,000 experts gathered at the 23rd Meeting of the European Neurological Society (ENS) in Barcelona to discuss the latest developments in the field. Prof Reichmann (University Hospital Carl...
Even experts can have a hard time determining the degree of consciousness that patients have following severe cranio-cerebral injuries. A team of researchers at the University of Liège in Belgium have discovered a new method for determining gradual degrees of consciousness. The major advantage...
Stories often appear in health communication in order to encourage individuals to change behaviors, such as smoking or not wearing sunscreen. A University of Missouri researcher studied how stories influence patients’ decision-making when behavior change is not the desired outcome of the health...
JAMA Neurology Study Highlights A study by Hans-Peter Hartung, M.D., of Heinrich-Heine-Universität, Düsseldoft, Germany, and colleagues examines the association between IL-17F and treatment response to interferon beta-1b among patients with relapsing-remitting multiple sclerosis. (Online...
Patients in hospital who are on antibiotics may benefit from taking probiotics, according to researchers at St. Michael’s Hospital.
Dr. Reena Pattani led a literature review that looked at the effectiveness of probiotics, live bacteria that can take up residence in digestive tracts, in...
A new study of young women with breast cancer has found that most chose to have a mastectomy rather than a surgical procedure that would conserve the breast, researchers report at the 49th Annual Meeting of the American Society of Clinical Oncology, May 31-June 4, in Chicago...
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A further report on the results of EORTC trial 26951 indicates that CpG island methylator phenotype (CIMP) status and O 6-methylguanine-DNA methyltransferase (MGMT) promoter methylation as assessed by MGMT-STP27 are the most informative for identifying grade III glioma patients who might benefit...
Human foetal stem cell grafts improve both motor and sensory functions in rats suffering from a spinal cord injury, according to research published this week in BioMed Central's open access journal Stem Cell Research and Therapy. This cell replacement therapy also improves the structural...
Coenzyme Q10 (CoQ10) cuts mortality by half in patients with heart failure, researchers from Denmark reported at the annual meeting of the Heart Failure Association of the European Society of Cardiology, which took place in Lisbon, Portugal this year. Professor Svend Aage Mortensen and team...
Johns Hopkins researchers have developed new guidelines - the first in more than 35 years - to govern the amount of blood ordered for surgical patients. The recommendations, based on a lengthy study of blood use at The Johns Hopkins Hospital (JHH), can potentially save the medical center more...
Patients with underlying heart failure are more likely to experience adverse outcomes from mild hypothyroidism, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Hypothyroidism occurs when an underactive thyroid...