Researchers from the Spanish National Cancer Research Centre (CNIO), led by Jorge L. MartÃ*nez-Torrecuadrada from the Proteomics Unit, have demonstrated that the antibody-based blocking of ephrinB2, a protein involved in angiogenesis and lymphoangiogenesis, may represent an effective strategy for the development of antiangiogenic and antitumoural therapies. The results of this study appeared in this month's issue of Blood, the journal of the American Society of Hematology. CNIO researchers generated highly-specific human antibodies against ephrin-B2 using a phage display approach...
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