The ability to maintain mental representations of ourselves and the world - the fundamental building block of human cognition - arises from the firing of highly evolved neuronal circuits, a process that is weakened in schizophrenia. In a new study, researchers at Yale University School of Medicine pinpoint key molecular actions of proteins that allow the creation of mental representations necessary for higher cognition that are genetically altered in schizophrenia. The study was released in the Proceedings of the National Academy of Sciences...
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