In a laboratory, preclinical study recently published by the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers combined structural features from anti-nausea drug thalidomide with common kitchen spice turmeric to create hybrid molecules...
CHOP researchers advance stem cell studies in a childhood leukemia and diamond blackfan anemia First produced only in the past decade, human induced pluripotent stem cells (iPSCs) are capable of developing into many or even all human cell types. In new research, scientists reprogrammed skin...
An international collaboration of researchers including Felicia Goodrum of the University of Arizona's immunobiology department has studied how a human herpes virus carried by the majority of the population packages its genetic information during infection. The discoveries improve the chances of...
In a new paper published in the journal Nature, researchers present a previously unknown mechanism that controls whether a cell survives autophagy, a process that can be compared to the cell consuming parts of itself. The discovery means that it might now be possible to influence the process...
Cells from one's own blood could be converted into a treatment for autoimmune diseases, like rheumatoid arthritis and Crohn's disease, based on the discovery of a Purdue University researcher. Chang Kim, a professor of comparative pathobiology, has created a way to direct the differentiation of...
Researchers in China announced in a paper published in the journal Science on Thursday that they have developed an "easy and safe" way to make stem cells that could rekindle the great hope for growing tissue and organs from stem cells to treat a range of diseases. By using a cocktail of small...
Here’s a good reason to pay attention in math class. Nature Communications has published a paper from Ottawa researchers today, outlining how advanced mathematical modelling can be used in the fight against cancer.
The technique predicts how different treatments and genetic modifications might...
Scientists are reporting development and successful lab tests on the first potential drug to pack a lethal one-two punch against melanoma skin cancer cells. Hit number one destroys cells in the main tumor, and the second hit blocks the spread of the cancer to other sites in the body, according...
Two new studies published in Nature recently reveal the structure and mechanism of an enzyme called cGAS that detects DNA found in the wrong place inside mammal cells and triggers an immune response. The researchers believe their findings open avenues for developing new cancer and autoimmune...
Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails. The new finding, by a team of University of Wisconsin School of Medicine...
Finding could reduce need for blood donations, speed up research on therapies to treat diseases A study led by Boston University School of Medicine has identified a novel approach to create an unlimited number of human red blood cells and platelets in vitro. In collaboration with Boston...
Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails.
The new finding, by a team of University of Wisconsin School of Medicine...
Cancers of all types become most deadly when they metastasize and spread tumors throughout the body. Once cancer has reached this stage, it becomes very difficult for doctors to locate and treat the numerous tumors that can develop. Now, researchers at the University of Missouri have found a way...
When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious...
Scientists at Oregon Health & Science University and the Oregon National Primate Research Center (ONPRC) have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell type in the body. It is believed that stem cell therapies hold the...
When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ravaged their DNA. A new finding from MIT researchers may offer a way to overcome that...
Fred Hutchinson Cancer Research Center and University of Washington scientists have identified a class of immune cells that reside long-term in the genital skin and mucosa and are believed to be responsible for suppressing recurring outbreaks of genital herpes.
These immune cells also play a...
A University of Wisconsin-Madison research group has converted skin cells from people and monkeys into a cell that can form a wide variety of nervous-system cells - without passing through the do-it-all stage called the induced pluripotent stem cell, or iPSC. Bypassing the ultraflexible iPSC...
Stem cells drawn from amniotic fluid show promise for tissue engineering, but it's important to know what they can and cannot do. A new study by researchers at Rice University and Texas Children's Hospital has shown that these stem cells can communicate with mature heart cells and form...