How to fix a p0300 random/multiple cylinder misfire detected on a 2004 2.4L

For the most part misfiring is caused by one of three conditions; these include loss of compression, loss of spark and a fuel / air mixture that is out of parameters.

Some potential reasons for loss of compression can include burnt valve(s), blown head gasket or worn or cracked piston rings.

Loss of spark can be due to a weak or failing coil, cracked distributor cap, bad spark plug, or failing ignition module.

An out of parameter fuel / air mixture can be due to a vacuum leak, dirty, leaking EGR valve, low fuel pressure, defective fuel pressure regulator or failing fuel pump.

give her a tune up! plugs wires coil-packs.still misses after that need a compresson tester