Cells with too few or too many chromosomes have long been known to be a hallmark of cancer - but the cause of this abnormal number of chromosomes has been little understood. Now, in Science, researchers at the Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center, have identified a gene that is commonly mutated in human cancers and have demonstrated its direct role in causing aneuploidy, an abnormal number of chromosomes...
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