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    Boston Children's launches Phase I clinical trial of long-lasting local anesthetic de

    Boston Children's Hospital has received Investigational New Drug (IND) approval from the US Food and Drug Administration (FDA) for neosaxitoxin, a new local anesthetic derived from cyanobacteria being developed in partnership with Proteus SA, of Santiago, Chile. With the IND approval in hand...
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    Phase II clinical study with melflufen in the treatment of multiple myeloma patients

    Oncopeptides AB, a company working to enhance oncology therapies, today announced that the first patient has been dosed as part of a Phase II study in multiple myeloma patients with its drug candidate melflufen (previously called J1). The trial is an open-label Phase II study designed to...
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    New Sickle Cell Anemia Therapy Advances To Phase II Clinical Trials

    Seeking to improve the lives of sickle cell anemia sufferers around the world, researchers from the La Jolla Institute for Allergy and Immunology, the Dana-Farber/Children's Hospital Cancer Center in Boston and the BloodCenter of Wisconsin in Milwaukee and others are preparing to launch Phase II...
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    Phase I Clinical Trial For An H5N1 Bird Flu Vaccine Shows Positive Results

    IDRI (Infectious Disease Research Institute), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc. (TSX: MDG; OTCQX: MDCGF), a biopharmaceutical company focused on developing highly effective...
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    Neurim Pharmaceuticals Announces Positive Phase 2 Clinical Trial Results Of Piromelat

    Neurim Pharmaceuticals have announced positive results from a phase II clinical study evaluating the efficacy and safety of Piromelatine (Neu-P11), a novel investigational multimodal sleep medicine developed for the treatment of patients with primary and co-morbid insomnia. The new results are...
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    Phase II Trial Shows Selumetinib Reverses Radioiodine Resistance In Some Advanced Thy

    The experimental drug selumetinib may allow some patients with advanced thyroid cancer to overcome resistance to radioiodine (RAI), the most effective therapy for the disease, according to new research from Memorial Sloan-Kettering Cancer Center. Published in the February 14 issue of the New...
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    Acute Heart Failure Phase III Clinical Trial Designed To Assess Early Treatment On Ca

    Cardiorentis has initiated the first-ever acute heart failure (AHF) Phase III trial to be specifically designed to assess the effect of early treatment on cardiovascular mortality. TRUE-AHF (TRial of Ularitide's Efficacy and safety in patients with Acute Heart Failure) aims to show that early...
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    Phase 2 Clinical Trial Of Ibrutinib Shows High Overall Response, Remissions In Patien

    An international study of ibrutinib in people with relapsed or refractory mantle cell lymphoma (MCL) continues to show unprecedented and durable results with few side effects. Researchers from The University of Texas MD Anderson Cancer Center presented interim findings of the multi-center Phase...
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    Boehringer Ingelheim To Initiate Phase III Study In Leukaemia With Its Compound Volas

    New positive Phase II results from an interim analysis of the randomised Phase I/II study involving the company's investigational haematology/oncology compound volasertib* in newly diagnosed patients with acute myeloid leukemia (AML) considered ineligible for intensive remission induction...
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    Cx601 Phase I/IIa Study Published In International Journal Of Colorectal Disease

    TiGenix (Euronext Brussels: TIG) have announced the publication in the International Journal of Colorectal Disease of the Phase I/II study of Cx601: Expanded allogeneic adipose-derived stems cells (eASCs) for the treatment of complex perianal fistula in Crohn's disease: results from a...
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    Drugmaker Begins Phase I Clinical Trial To Test Microtubule Stabilizing-Drug In Mild

    While clinical trial results are being released regarding drugs intended to decrease amyloid production - thought to contribute to decline in Alzheimer's disease - clinical trials of drugs targeting other disease proteins, such as tau, are in their initial phases... More...
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    Ultra-Long-Acting Insulin Degludec, Two Phase 3 Studies Published

    Two Phase III studies, published in The Lancet, reveal that ultra-long-acting insulin degludec considerably reduced rates of nocturnal hypoglycemia in patients with type 1 and type 2 diabetes by 25%, compared to insulin glargine. Insulin degludec is an investigational compound developed by Novo...
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    Quiz: What Lunar Phase Are You?

    I got: You Are the Waxing Moon You are most aligned with the waxing moon which represents new possibilities and nourishment. You're incredibly kind, caring, and generous. You naturally put others first. You appreciate a simple quiet moment. You can relax easily without feeling bored. You are a...
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    Bionovo Initiates Menerba (MF101) Phase 3 Clinical Trial For Menopausal Hot Flashes

    Bionovo, Inc. (Nasdaq: BNVI), a pharmaceutical company focused on the discovery and development of safe and effective treatments for women's health and cancer, announced that enrollment has started to the Phase 3 pivotal clinical trial evaluating the safety and efficacy of two doses of Menerba™...
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    Puma Biotechnology Announces Positive PB272 (Neratinib) Phase II Data At CTRC-AACR Sa

    Puma Biotechnology, Inc., a development stage biopharmaceutical company, announced that results from ongoing Phase II clinical trials of Puma's investigational drug PB272 (neratinib) were presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium that is currently taking place in San...
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    Nutrition during a Bulking Phase?

    So I recently embarked on a muscle building routine. However, I have one worry. I know that to gain muscle, you are required to eat at least 500 calories above your regular assigned calorie intake. My question is, what if I am unable to make it to the gym during the week for whatever reason...
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    12-Week On-Treatment Results From Large Phase IIb Study (COMMAND-1) Of Bristol-Myers

    Bristol-Myers Squibb Company (NYSE: BMY) announced interim results from a Phase IIb clinical trial (COMMAND-1) of 395 treatment-naïve, genotype 1 and 4 hepatitis C infected patients in which two doses of the investigational NS5A replication complex inhibitor daclatasvir (BMS-790052), in...
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    Boyfriend Issue: losing interest? or just a phase?

    I have been with my bf for over 2 years now and I was very much in love. . The other night we had a discussion that was completely opposite from what my understanding so far. We had everything planned out and even joked about marriage and children. I told him that I would want to marry young (24...
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    Advanced Prostate Cancer With Bone Metastases Survival Improved In First Phase III Tr

    According to an investigation reported today at the 2011 European Multidisciplinary Cancer Congress, individuals suffering with bone metastases from advanced prostate cancer have not had many options until recently. Now the first Phase II investigation of an alpha-pharmaceutical in these...
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    Results Of A Pivotal Phase 3 Efficacy And Safety Study For Butrans® (Buprenorphine) T

    Butrans® (Buprenorphine) Transdermal System CIII 20 mcg/hour provided significantly lower "average pain over the last 24 hours" scores compared to Butrans 5 mcg/hour when used in opioid-experienced patients with moderate-to-severe chronic low back pain, according to a pivotal Phase 3 clinical...
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