Researchers conducting a preclinical study in mice successfully used targeted molecular therapy to block mostly untreatable nerve tumors that develop in people with the genetic disorder Neurofibromatosis 1 (NF1). Scientists from Cincinnati Children's Hospital Medical Center report their...
Scientists at the Gladstone Institutes have defined for the first time a key underlying process implicated in multiple sclerosis (MS) - a disease that causes progressive and irreversible damage to nerve cells in the brain and spinal cord. This discovery offers new hope for the millions who...
It's a high-pressure environment within solid tumors. Abnormal blood and lymphatic vessels cause fluids to accumulate, and the uncontrolled proliferation of cancer cells within limited space leads to the buildup of what is called solid stress. Both types of pressure can interfere with the...
Researchers in the University of Leicester's Department of Cell Physiology and Pharmacology have identified a cellular mechanism that could underlie the development of tinnitus following exposure to loud noises. The discovery could lead to novel tinnitus treatments, and investigations into...
Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ends by telomerase, an enzyme thought to play a key role in cancer and...
Very young children who live in a home with a swimming pool are at risk of drowning, a leading cause of injury death among toddlers. A study abstract presented Monday, Oct. 17, at the American Academy of Pediatrics (AAP) National Conference and Exhibition in Boston identifies three likely...
An international consortium of scientists reports the discovery of five new genes that affect the risk of developing coronary artery disease (CAD) and heart attacks in a study published in the open-access journal PLoS Genetics. Coronary artery disease is the most common cause of premature death...
A report of a study investigating over the counter medicine (OTC) abuse published by the Pharmacy Practice Research Trust provides evidence that there is a group of individuals experiencing a range of problems often with codeine-based medicines purchased from pharmacies, and for whom help and...
The journal Radiology will publish in its September issue an article written by Damian E. Dupuy, M.D., director of tumor ablation at Rhode Island Hospital, supporting the use of ablation procedures for the treatment of lung cancer. The article, "Image-guided Thermal Ablation of Lung...
Today's rapid economic change and labor market turbulence make early careers particularly unstable, but new research to be presented at the 106th Annual Meeting of the American Sociological Association shows that young workers with certain characteristics may weather turbulent times better than...
The recent outbreak of an E. coli infection in Germany has resulted in serious concerns about the potential appearance of a new deadly strain of bacteria. In response to this situation, and immediately after the reports of deaths, the University Medical Centre Hamburg-Eppendorf and BGI-Shenzhen...
Cancer researchers at the Kimmel Cancer Center at Jefferson and an international team of collaborators have discovered a biomarker in breast cancer that may help identify which women will respond to anti-estrogen therapy. The research appears in the May 16 online issue of the Journal of...
In light of the recent historic Medicare fraud bust, a new analysis that examines the "Seven Guiding Principles for Policymakers" to fighting health care fraud invites new questions about legislative efforts to reduce accountability and oversight of independent pharmacies, the Pharmaceutical...
Repairing small, seemingly benign holes in a child's heart may be more clinically important than previously thought, as dysfunction could be lurking out of sight. These are the findings from a study conducted by doctors and researchers at Nationwide Children's Hospital and the Ohio State...
The FDA inspected 0.7 percent of foreign clinical drug trial sites in 2008 while 80 percent of applications approved for marketing that year contained data from foreign drug trials, according to a report (.pdf) from the Inspector General of HHS, CBS News reports (Strickler, 6/22). Companies...
Researchers have long wondered why the people of the Tibetan Highlands can live at elevations that cause some humans to become life-threateningly ill - and a new study answers that mystery, in part, by showing that through thousands of years of natural selection, those hardy inhabitants of...
Results from the VeriStrat biomarker analysis of a multicenter Phase III trial were presented at the 2nd European Lung Cancer Conference currently being held in Geneva, Switzerland. Results showed that the VeriStrat test identified patients who were likely to have a survival benefit from...
Results of a new study in non-small cell lung cancer showed that patients with specific oncogenic rearrangements of the anaplastic lymphoma kinase (ALK) gene within the short arm of chromosome 2 of their tumors had a much greater response to a new therapy - an ALK-inhibitor. Findings were...
identify or be labeled as? I was wondering about this question for some time now, and I was wondering are those women two-spirit, third gender, or what?
Young men who believe that happiness declines with age are more likely to engage in risky health behaviors such as binge drinking. Their misguided negative view of the aging process may act as a disincentive to behave 'sensibly' and encourage them to make the most of the present in anticipation...