When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ravaged their DNA. A new finding from MIT researchers may offer a way to overcome that...
JAMA Psychiatry Study Highlights A study by Katherine L. Wisner, M.D., M.S., and colleagues screened postpartum women for depression and examined positive screening findings to determine the timing of the episode's onset, along with the rate and intensity of self-harm thoughts. (Online First)...
Researchers from Benaroya Research Institute at Virginia Mason (BRI) have found that proteins in the IL-6 signaling pathway may be leveraged as novel biomarkers of multiple sclerosis (MS) to gauge disease activity and as a target for new therapies. The research, which investigated how several...
Johns Hopkins scientists have created stunning images of the branching patterns of individual sensory nerve cells. Their report, published online in the journal eLife on Dec. 18, details the arrangement of these branches in skin from the backs of mice. The branching patterns define ten distinct...
'Direct to consumer' research, using data obtained through increasingly popular online communities such as 23andMe, PatientsLikeMe and the Personal Genome Project, has methodological limitations that are known to epidemiological studies, including selection bias, information bias, and...
As liver cancer develops, tumor cells lose the ability to produce and release glucose into the bloodstream, a key function of healthy liver cells for maintaining needed blood-sugar levels. The findings come from a study by scientists at The Ohio State Comprehensive Cancer Center - Arthur G...
Researchers have long been aware that the progressive loss of muscle mass and bone density is a natural part of aging. But little work has investigated how muscle tissue affects the inner and outer layers of bone microstructure. A Mayo Clinic study looked at skeletal muscle mass and bone health...
These findings are not about the classic story of gift-giving, although the MAGI genes (officially named membrane associated guanylate kinase, WW and PDZ domain containing proteins) do influence brain function in important ways. MAGI1 and MAGI2 are genes that code for the MAGI proteins. These...
New findings in breast cancer research by an international team of scientists contradict the prevailing belief that only basal-like cells with stem cell qualities can form invasive tumors. Research led by Ole William Petersen at the University of Copenhagen (CU) and Mina Bissell of the Lawrence...
Stroke patients receiving in-patient rehabilitation are more likely to land back in the hospital within three months if they are functioning poorly, show signs of depression and lack social support according to researchers at the University of Texas Medical Branch (UTMB) at Galveston. Hospital...
A two-year study of high school football players suggests that concussions are likely caused by many hits over time and not from a single blow to the head, as commonly believed. Purdue University researchers have studied football players for two seasons at Jefferson High School in Lafayette...
The University of Kentucky Markey Cancer Center breast oncologist Dr. Suleiman Massarweh and his research team presented findings from their studies on relapse of breast cancer at the San Antonio Breast Cancer Symposium this month. The two studies aimed to characterize further risk factors for...
According to a recent study published in the November issue of the Journal of the American College of Radiology, many radiologists disagree on the management of incidental findings found on body computed tomography (CT) scans. An incidental finding is something found that is unrelated to the...
Looks interesting, but so far my "highlighting" in ebooks is fairly quirky and has to do with specific objectives I have that others may not know. In other words, sharing them would be potentially problematic considering how easy and common it is to take anyone's words off the web and get all...
New findings about how the brain functions to suppress pain have been published in the leading journal Pain, by NUI Galway researchers. For the first time, it has been shown that the hippocampus of the brain, which is usually associated with memory, has an active role to play in suppressing pain...
NASA will hold a news conference at 1 p.m. EDT (10 a.m. PDT) on Thurs., Sept. 29, to reveal near-Earth asteroid findings and implications for future research. The briefing will take place at NASA Headquarters in Washington. NASA's Wide-field Infrared Survey Explorer (WISE) mission, launched in...
Using the latest gene sequencing tools to examine so-called epigenetic influences on the DNA makeup of colon cancer, a Johns Hopkins team says its results suggest cancer treatment might eventually be more tolerable and successful if therapies could focus on helping cancer cells get back to...
The capacity to remember that a zebra has stripes, or that a giraffe is a four-legged mammal, is known as semantic memory. It allows us to assign meaning to words and to recall general knowledge and concepts that we have learned. The deterioration of these capacities is a defining feature of...
It's just a worm, a tiny soil-dwelling nematode worm - but the implications are big for biomedicine and circadian biology as shown in a recent study authored by University of Nevada, Reno researcher Alexander van der Linden. The article on the circadian clock of the Caenorhabditis elegans worm...
A report into the care received by nearly 8,000 patients with dementia in 206 hospitals in England and Wales has revealed that few hospitals provide mandatory training for their staff in awareness of dementia, that many patients with dementia are not having assessments of their mental health or...