enzyme

  1. T

    High levels of a specific enzyme in mice fetuses linked to anxiety

    Mouse embryos with the human enzyme CYP2C19 in the brain develop a smaller hippocampus and anxiety-like behaviour as adults. The results of this new study, which is published in the journal Molecular Psychiatry, agree in principle with earlier genetic findings in humans, and can improve...
  2. T

    Enzyme That Finds Unwanted DNA In Cells Revealed

    Two new studies published in Nature recently reveal the structure and mechanism of an enzyme called cGAS that detects DNA found in the wrong place inside mammal cells and triggers an immune response. The researchers believe their findings open avenues for developing new cancer and autoimmune...
  3. G

    Depression linked to telomere enzyme, aging, chronic disease

    The first symptoms of major depression may be behavioral, but the common mental illness is based in biology — and not limited to the brain. In recent years some studies have linked major, long-term depression with life-threatening chronic disease and with earlier death, even after lifestyle risk...
  4. P

    My AST was 695 and my ALT was 560 - when my liver enzyme reading... what could

    cause this? Basically, I went to the hospital and my liver readings from my blood came back really high on all, all plus 400 except total protein which was 82, my AST was 695, my ALT, was 560, can anyone tell me why? or what they actually mean?
  5. K

    How do you work out enzyme activity of ALT from measured absobance values over time?

    I did a lab aimed to determine the Aspartate Aminotransferase activity in human plasma. We measured the absorbance of different concentrations of NADH and from this worked out the extinction coefficient of 5.713 (3dp) We also measured absorbance of a control sample and 2 patient samples. The...
  6. T

    Enzyme's Double Life Revealed - Critical Role In Cancer Blood Supply

    Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected - and critical - additional role in cancer metastasis in a study conducted collaboratively in the labs of Karen Lounsbury, Ph.D...
  7. T

    Protection Against Dangers Of Oxygen Offered By "Super" Enzyme

    Just like a comic book super hero, you could say that the enzyme superoxide dismutase (SOD1) has a secret identity. Since its discovery in 1969, scientists believed SOD1's only role was to protect living cells against damage from free radicals. Now, researchers at the Johns Hopkins Bloomberg...
  8. T

    Enzyme Helps Drive Aggressive Prostate Cancer

    Researchers at the Mayo Clinic in Florida have discovered that an enzyme called PRSS3, or mesotrypsin, may help drive aggressive prostate cancer. Although they don't believe it is the only factor, they suggest it offers a new target for treatment, and have themselves developed a prototype...
  9. T

    Gateway Enzyme For Chemicals From Catnip To Cancer Drug

    Scientists have discovered an enzyme used in nature to make powerful chemicals from catnip to a cancer drug, vinblastine. The discovery opens up the prospect of producing these chemicals cheaply and efficiently. They are produced naturally by some plants such as the medicinal Madagascar...
  10. T

    Inhibiting CaMKII Enzyme Activity Could Lead To New Therapies For Heart Disease

    University of Iowa researchers have previously shown that an enzyme called CaM kinase II plays a pivotal role in the death of heart cells following a heart attack or other conditions that damage or stress heart muscle. Loss of beating heart cells is generally permanent and leads to heart...
  11. T

    Discovery Of New Immune Defence Enzyme

    Neutrophil granulocytes comprise important defences for the immune system. When pathogenic bacteria penetrate the body, they are the first on the scene to mobilise other immune cells via signal molecules, thereby containing the risk. To this end, they release serine proteases - enzymes that cut...
  12. T

    Metabolism Boosted By Enzyme, Weight Gain Prevented In Mice

    Male and female mice engineered to express the inflammatory enzyme IKKbeta in their fat tissue ate more but gained less weight. They burned sugar and fat more effectively than mice who were left unaltered. The research may shed light on how obesity and inflammation affect insulin resistance and...
  13. T

    Enzyme Controlling Cell Death Paves Way For Treatment Of Brain Damage In Newborns

    Brain damage due to birth asphyxia where the brain is starved of oxygen around the time of delivery is normally treated by cooling the infant, but this only helps one baby in nine. New research from the Sahlgrenska Academy at the University of Gothenburg, Sweden, could now pave the way for new...
  14. T

    Enzyme's Structure Reveals Basis For Head, Sex Organ Deformities

    Scientists this month reported the molecular structural basis for severe head deformities and ambiguous sex organs in babies born with Antley-Bixler syndrome accompanied by an enzyme deficiency. The team, composed of researchers from The University of Texas Health Science Center San Antonio, the...
  15. T

    Blocking Receptor In Key Hormone Fires Up Enzyme To Kill Pancreatic Cancer Cells

    Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell...
  16. J

    How to start introduction for biology enzyme SAC?

    The enzyme is called Diastase (an amylase) <-- What does amylase mean? Introduction should cover... Function of enzymes Effect of diastase on starch Sensitivity of enzymes to varying factors
  17. T

    Lightly Steamed Broccoli Has Powerful Anticancer Enzyme Myrosinase

    Broccoli can significantly reduce your risk of developing cancers if you don't destroy the enzyme myrosinase - you can only do this effectively by steaming the vegetable lightly. Overcook it and the health benefits will be considerably undermined, researchers from the University of Illinois...
  18. B

    The polymerase chain reaction requires a heat-resistant enzyme. What is the

    relationship between this fact and? a. Heat-resistant bacteria in hot springs can initiate the polymerase chain reaction. b, Heat-resistant enzymes can be extracted from heat-resistant bacteria growing in Yellowstone National Park hot springs. c. Hot springs vary in temperature just like...
  19. T

    New Clue In Leukemia Mystery: Researchers Identify "Poison" Employed By Deadly Enzyme

    New Clue In Leukemia Mystery: Researchers Identify "Poison" Employed By Deadly Enzyme There is new hope for people with acute myelogenous leukemia (AML), a fast-growing cancer of the blood and bone marrow. Research led by Weill Cornell Medical College and published today in the online edition...
  20. T

    Head And Neck Cancer: Enzyme Found To Be A Predictive Marker Of Survival

    Most treatment for advanced head and neck cancer requires chemotherapy with a drug called cisplatin, an inorganic platinum agent that inhibits cell growth. A substantial number of patients do not respond well to this therapy, but oncologists are unable to prescribe alternative agents because...
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