A versatile mouse that can teach us about many diseases and drugs

tD33NAt

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Mar 24, 2008
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Scientists from the UK and Australia have created a mouse that expresses a fluorescing 'biosensor' in every cell of its body, allowing diseased cells and drugs to be tracked and evaluated in real time and in three dimensions.This biosensor mimics the action of a target molecule, in this case a protein known as 'Rac', which drives cell movement in many types of cancer. Rac behaves like a switch, oscillating on the molecular level between two states - active or inactive. When Rac is active, the biosensor picks up chemical cues and glows blue.
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