The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body. Now, researchers at Sanford-Burnham Medical Research Institute have described the molecular and cellular pathway that leads to this hardening of the arteries - and zeroed in on a particularly destructive protein called Dkk1. Their study was published online today by Arteriosclerosis, Thrombosis, and Vascular Biology...
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