According to a study published in the February 8 issue of JAMA, cefpodoxime, an antibiotic used as a short-term therapy in women with uncomplicated bladder infection (cystitis), failed to meet criteria for non-inferiority in comparison to ciprofloxacin. There have been concerns that ciprofloxacin, classed as a fluoroquinolone antibiotic, is overused, resulting in an increase in resistance rates. The criteria for non-inferiority were defined as cefpodoxime's efficacy lying within a pre-specified margin of 10% of ciprofloxacin's efficacy...

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