I have tried everything on the market for knee pain due to arthritis Dr has given up He does not know what to try Does anyone have any ideas I have been told I need replacement joints but need to lose weight first. I am unable to stand after sitting awhile. Taking a step is most impossible at times. any thing that has worked either an RX or over the counter. Doc has said other joints will start to act the same. Wrist and ankles hurt some now. Any help appreciated. I have used naprocin Bextra Celebrex and many others nothing works.