Although we know that mild cognitive impairment is a transitional stage between normal aging and Alzheimer's disease, changes in brain networks during this transformation have yet to be studied. Dr. Jie Xiang and colleagues from Taiyuan University of Technology, China constructed brain networks using resting-state functional MRI data that were extracted from four populations (normal controls, patients with early mild cognitive impairment, patients with late mild cognitive impairment, and patients with Alzheimer's disease) using the Alzheimer's Disease Neuroimaging Initiative data set.

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