Making use of a new "super resolution" microscope that provides sharp images at extremely small scales, scientists have achieved unprecedented views of the immune system in action. The new tool, a stimulated emission depletion (STED) microscope, shows how granules from natural killer cells pass through openings in dynamic cell structures to destroy their targets: tumor cells and cells infected by viruses. Deeper understanding of these biological events may allow scientists to devise more effective treatments for inherited diseases that impair the immune system...

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