A mosquito-borne virus that kills about half of the people it infects uses a never-before-documented mechanism to "hijack" one of the cellular regulatory systems of its hosts to suppress immunity, according to University of Pittsburgh Center for Vaccine Research scientists. The discovery, which will be published in the journal Nature and is funded by the National Institutes of Health (NIH), could aid in the development of vaccines and treatments for eastern equine encephalitis virus (EEEV), a rare but deadly disease that is found primarily in the Atlantic and Gulf States.

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