It has long been known that breast density, or mammographic density, is a strong risk factor for breast cancer, and that estrogen and progestin hormone therapy increases dense breast tissue. Now, a study published in BioMed Central's open access journal Breast Cancer Research has identified several gene variants in hormone metabolism and growth factor pathways that may be associated with breast density and, hence, breast cancer risk. Mammographic density relates to the fact that x-rays permeate different types of breast tissue in different ways, leading to white areas on the mammogram...
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