Seeking to improve the lives of sickle cell anemia sufferers around the world, researchers from the La Jolla Institute for Allergy and Immunology, the Dana-Farber/Children's Hospital Cancer Center in Boston and the BloodCenter of Wisconsin in Milwaukee and others are preparing to launch Phase II...
Pain is an undeniable focal point for patients with sickle cell disease but it's not the best focus for drug development, says one of the dying breed of physicians specializing in the condition. Rather scientists need to get back to the crux of the disease affecting 1 in 500 black Americans and...
A new mouse study, published in this week's early online issue of the Proceedings of the National Academy of Sciences, appears to have discovered a way to trigger production of red blood cells, raising hope of a potential new treatment for preventing the painful episodes and organ damage often...
Not long after birth, human babies transition from producing blood containing oxygen-rich fetal hemoglobin to blood bearing the adult hemoglobin protein. For children with sickle cell disease, the transition from the fetal to adult form of hemoglobin - the oxygen-carrying protein in blood -...
The multicenter Baby HUG trial led by St. Jude Children's Research Hospital investigators shows hydroxyurea reduces the most common symptoms of sickle cell anemia in children, raising hopes the drug will ease complications and improve patient quality of life. New research shows a drug...
I'm trying to write about how heterozygote advantage of sickle cell anemia has led to increased population in heterozygous (sickle-cell carriers) individuals.
If there is any legitimate data that shows increased number in carriers in the last however long, it'd be greatly appreciated.
A University of Minnesota Medical School research team led by Kalpna Gupta, Ph.D., has discovered that cannibinoids offer a novel approach to ease the chronic and acute pain caused by sickle cell disease (SCD). Using a mouse model of SCD, Gupta and University of Minnesota colleagues studied the...
Researchers from the La Jolla Institute for Allergy & Immunology have joined forces with the Dana-Farber Cancer Institute in Boston and Washington University in St. Louis to investigate a potential new therapy for sickle cell disease, a severe and chronic illness affecting more than 70,000...
Infection with the H1N1 virus, or swine flu, causes more life-threatening complications than seasonal flu in children with sickle cell disease, according to research from Johns Hopkins Children's Center. The findings, to be presented on Dec. 7 at the annual meeting of the American Society of...
...has only deleterious effects? You know, sickle cell anemia, that evolutionary adaptation that allowed humans to have resistance to malaria.
Is religion an evolutionary adaptation that was once useful to self-aware hominids dealing with a a mystifying, terrifying world? That is now just a...