Researchers at Karolinska Institutet in Sweden have found a promising strategy for defeating neuroblastoma - a malignant form of cancer in children - that focuses on the so-called MYCN protein. A specific chemical molecule helps to break down MYCN, which either kills the cancer cell or makes it...
Nearly two-thirds of patients with high-risk neuroblastoma - a common tumor that forms in the nerve cells of children - cannot be cured using tumor-killing cancer drugs. A study published by Cell Press in the journal Chemistry & Biology reveals a new genomic approach to screen for compounds that...
A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma. A phase 1 clinical trial of the drug crizotinib achieved...